Search
Best hotels
Best value
When to book
Tips
FAQs
Map

Hotels in Otay Mesa, San Diego

Thu 6/20
Fri 6/21

Search hundreds of travel sites at once for hotels in Otay Mesa

Here is why travelers choose KAYAK

Free to useThere are no hidden charges or fees.

Filter your dealsFilter by free cancellation, free breakfast and more.

Millions of reviewsCheck ratings based on millions of real guest reviews.

Bundle and saveSave money when you bundle your flight + hotel.

Best hotels in Otay Mesa (San Diego)

Most recommended Otay Mesa hotels

Show all
Holiday Inn Express & Suites San Diego Otay Mesa - San Diego - Pool
Holiday Inn Express & Suites San Diego Otay Mesa
5.9 Fair
Otay Mesa$198+
$198+
Free Wi-Fi
Pool
Quality Suites San Diego Otay Mesa - San Diego - Bedroom
Quality Suites San Diego Otay Mesa
6.8 Okay
Otay Mesa$159+
$159+
Parking
Free Wi-Fi
Pool
AAAmazing San Diego! Suite just for you/yours! - San Diego
AAAmazing San Diego! Suite just for you/yours! - San Diego
AAAmazing San Diego! Suite just for you/yours!
Otay Mesa$315+
$315+
Free Wi-Fi
Pool
Go to map

Search by stars

2+ stars

Search by review score

6+ Okay7+ Good8+ Great9+ Excellent

Search by price

$112 - $163$163 - $214$214 - $265$265 - $315$315+ per night

Search by freebies

Free cancellationFree breakfastFree parkingFree internet

How much is a Otay Mesa hotel?

Here are our most popular & best value hotels

2 stars and below

Good to know

Low season

November

High season

July

Average price (weeknight)

$111

Average price (weekend night)

$140
Cheapest month to stay with an average 26% drop in price.
Most expensive month to stay with an average 42% rise in price.
Average Sun - Thu price over the last 2 weeks.
Average Fri & Sat price over the last 2 weeks.

When to book a hotel in Otay Mesa

Price per night / 3-star hotel. Prices are not fixed and may vary with time.
Average nightly price per month
Average nightly price

Top tips for finding a hotel deal in Otay Mesa

  • If you’re looking for a cheap hotel in Otay Mesa, you should consider going during the low season. You’ll generally find lower-priced hotels in Otay Mesa in November and June.
  • If you’re looking for a bargain then KAYAK data shows that you’ll find the best hotel deals in Otay Mesa (San Diego) if you stay on a Thursday. On the other hand, the most expensive day for hotel bookings is Friday.
  • For the lowest prices, try to book your Otay Mesa hotel more than 90 days before your stay.
  • If you’re looking for a last minute bargain, the cheapest 3-star hotel in Otay Mesa (San Diego) found on KAYAK in the last 2 weeks was $152, while the most expensive was $173.
  • Not sure just how much there is to see and do in Otay Mesa? KAYAK users usually book their hotel here for 2 days.

FAQs when booking a hotel in Otay Mesa

  • What are the best hotels in Otay Mesa?

    Otay Mesa is a great part of San Diego to make your base. If you’re staying in Otay Mesa area then Quality Suites San Diego Otay Mesa, Holiday Inn Express & Suites San Diego Otay Mesa, and AAAmazing San Diego! Suite just for you/yours! are all recommended on KAYAK.

  • How much does a hotel in Otay Mesa (San Diego) cost?

    The average price for a hotel room in Otay Mesa is $126 but our users have found deals for as low as $111. However, hotel prices in Otay Mesa vary a lot depending on the type of hotel, the time of year and more factors.

Where to stay in Otay Mesa?

Our map will help you find the perfect hotel in Otay Mesa, San Diego by showing you the exact location of each hotel.

Popular in San Diego

Stays in San Diego

Airports in San Diego

Landmarks in San Diego

Venues in San Diego

Neighborhoods in San Diego